Toolkit for the analysis of multi-state QTL data


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Documentation for package ‘multistateQTL’ version 2.1.1

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callSignificance Call associations as significant in each state.
callSignificance-method Call associations as significant in each state.
callSignificance<- Call associations as significant in each state.
getComplete Filter QTLExperiment based on missing data
getSignificant Filter to only QTLs significant in at least one state
getTopHits Filter QTLExperiment to keep only top hits
plotCompareStates Compare QTL between two states
plotPairwiseSharing Heatmap of pairwise QTL sharing with state-level annotations
plotQTLClusters Heatmap of QTL across states
plotSimulationParams Distribution of estimated simulation parameters
plotUpSet Upset plot of QTL sharing between states with state-level annotations
qtleEstimate Estimate parameters from real data for simulating multi-state QTL summary statistics
qtleParams Default qtle simulation parameters
qtleParams2 Estimate parameters from real data for simulating multi-state QTL summary statistics
qtleSimulate Create simulated multistateQTL data for testing purposes
replaceNAs Return multistateQTL object with NAs filled in
runPairwiseSharing Compute the proportion of (significant) QTL shared by pairs of conditions
runSignificantFeatures Function to summarize QTL summary statistics by feature ID
runTestMetrics Classify multi-state QTL
simPerformance Performance metrics for multistateQTL simulations