Preprocessing, analyzing, and reporting of RNA-seq data


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Documentation for package ‘hermes’ version 1.13.0

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A C D E F G H I L M N O P Q R S T V W misc

hermes-package 'hermes' Package

-- A --

add_quality_flags Add Quality Flags
all_na Checks Whether All Missing
annotation Annotation Accessor and Setter
annotation-method Annotation Accessor and Setter
annotation<--method Annotation Accessor and Setter
AnyHermesData 'HermesData' and 'RangedHermesData'
AnyHermesData-class 'HermesData' and 'RangedHermesData'
assertions Additional Assertions for 'assert_that'
assertion_arguments Standard Assertion Arguments
assert_proportion Check for proportion
autoplot-method Correlation between Sample Counts of 'AnyHermesData'
autoplot-method Differential Expression Analysis
autoplot-method Correlation of Principal Components with Sample Variables
autoplot-method All Standard Plots in Default Setting
autoplot-method Derivation of Top Genes

-- C --

calc_cor Correlation between Sample Counts of 'AnyHermesData'
calc_pca Principal Components Analysis Calculation
cat_with_newline Concatenate and Print with Newline
cbind Column Binding of 'AnyHermesData' Objects
check_proportion Check for proportion
colMeanZscores Mean Z-score Gene Signature
colPrinComp1 First Principal Component (PC1) Gene Signature
col_data_with_genes Sample Variables with Selected Gene Information
ConnectionBiomart Connection to 'BioMart'
ConnectionBiomart-class Connection to 'BioMart'
connect_biomart Connection to 'BioMart'
control_normalize Control Settings for Counts Normalization
control_quality Control for Specified Quality Flags
correlate Generic Function for Correlation Calculations
correlate-method Correlation between Sample Counts of 'AnyHermesData'
correlate-method Correlation of Principal Components with Sample Variables
counts Counts Accessor and Setter
counts-method Counts Accessor and Setter
counts<--method Counts Accessor and Setter
cut_quantile Cutting a Numeric Vector into a Factor of Quantile Bins

-- D --

df_cols_to_factor Conversion of Eligible Columns to Factor Variables in a 'DataFrame'
diff_expression Differential Expression Analysis
draw_barplot Barplot for Gene Expression Percentiles
draw_boxplot Boxplot for Gene Expression Values
draw_genes_barplot Stacked Barplot of Low Expression Genes by Chromosome
draw_heatmap Heatmap for Gene Expression Counts
draw_libsize_densities Density Plot of (Log) Counts Distributions
draw_libsize_hist Histogram of Library Sizes
draw_libsize_qq Q-Q Plot of Library Sizes
draw_nonzero_boxplot Boxplot of Non-Zero Genes
draw_scatterplot Scatterplot for Gene Expression Values

-- E --

expect_proportion Check for proportion
expression_set Example 'ExpressionSet' Data
extraColDataNames Extra Variable Names Accessor Methods
extraColDataNames-method Extra Variable Names Accessor Methods
extraRowDataNames Extra Variable Names Accessor Methods
extraRowDataNames-method Extra Variable Names Accessor Methods
extra_data_names Extra Variable Names Accessor Methods

-- F --

filter Filter 'AnyHermesData' on Subset Passing Default QC Flags
filter-method Filter 'AnyHermesData' on Subset Passing Default QC Flags

-- G --

genes Gene IDs Accessor
genes-method Gene IDs Accessor
GeneSpec R6 Class Representing a Gene (Signature) Specification
gene_spec 'GeneSpec' Constructor
get_low_depth Add Quality Flags
get_low_expression Add Quality Flags
get_tech_failure Add Quality Flags

-- H --

hermes 'hermes' Package
HermesData 'HermesData' and 'RangedHermesData'
HermesData-class 'HermesData' and 'RangedHermesData'
HermesDataCor Correlation between Sample Counts of 'AnyHermesData'
HermesDataCor-class Correlation between Sample Counts of 'AnyHermesData'
HermesDataDiffExpr Differential Expression Analysis
HermesDataDiffExpr-class Differential Expression Analysis
HermesDataFromMatrix 'HermesData' and 'RangedHermesData'
HermesDataPca Principal Components Analysis Calculation
HermesDataPca-class Principal Components Analysis Calculation
HermesDataPcaCor Correlation of Principal Components with Sample Variables
HermesDataPcaCor-class Correlation of Principal Components with Sample Variables
HermesDataSummary Summary Method for 'AnyHermesData' Objects
HermesDataSummary-class Summary Method for 'AnyHermesData' Objects
HermesDataTopGenes Derivation of Top Genes
HermesDataTopGenes-class Derivation of Top Genes
hermes_data Example 'HermesData' Data
h_all_duplicated Finding All Duplicates in Vector
h_cpm Normalization of 'AnyHermesData' Objects
h_df_factors_with_explicit_na Conversion to Factors with Explicit Missing Level in a 'data.frame'
h_diff_expr_deseq2 'DESeq2' Differential Expression Analysis
h_diff_expr_voom 'limma'/voom Differential Expression Analysis
h_draw_boxplot_df Boxplot for Gene Expression Values
h_ensembl_to_entrez_ids Translation of 'Ensembl' to 'Entrez' Gene IDs
h_get_annotation_biomart Get Annotations from 'BioMart'
h_get_granges_by_id Conversion of 'BioMart' Coordinates into 'GRanges'
h_get_size_biomart Total Length of All Exons for Genes
h_has_req_annotations Predicate for Required Annotations
h_low_depth_flag Add Quality Flags
h_low_expression_flag Add Quality Flags
h_map_pos Helper Function For Matching Map Values to Names
h_parens Parenthesize a Character Vector
h_pca_df_r2_matrix Calculation of R2 Matrix between Sample Variables and Principal Components
h_pca_var_rsquared Calculation of R2 between Sample Variable and Principal Components
h_rlog Normalization of 'AnyHermesData' Objects
h_rpkm Normalization of 'AnyHermesData' Objects
h_short_list Make a Short List of a Character Vector
h_strip_prefix Stripping Prefix from Gene IDs
h_tech_failure_flag Add Quality Flags
h_tpm Normalization of 'AnyHermesData' Objects
h_unique_labels Creation of Unique Labels
h_voom Normalization of 'AnyHermesData' Objects
h_vst Normalization of 'AnyHermesData' Objects

-- I --

inner_join_cdisc Inner Joining a Genes with a CDISC Data Set
isEmpty Checking for Empty 'SummarizedExperiment'
isEmpty-method Checking for Empty 'SummarizedExperiment'
is_class Additional Assertions for 'assert_that'
is_constant Additional Assertions for 'assert_that'
is_counts_vector Additional Assertions for 'assert_that'
is_hermes_data Additional Assertions for 'assert_that'
is_list_with Additional Assertions for 'assert_that'

-- L --

lapply 'lapply' method for 'MultiAssayExperiment'
lapply-method 'lapply' method for 'MultiAssayExperiment'

-- M --

metadata Metadata Accessor and Setter
multi_assay_experiment Example 'MultiAssayExperiment' Data

-- N --

normalize Normalization of 'AnyHermesData' Objects
normalize-method Normalization of 'AnyHermesData' Objects

-- O --

one_provided Additional Assertions for 'assert_that'

-- P --

pca_cor_samplevar Correlation of Principal Components with Sample Variables
plot_all All Standard Plots in Default Setting
prefix Prefix Accessor

-- Q --

query Query Gene Annotations from a Connection
query-method Query Gene Annotations from a Connection

-- R --

RangedHermesData 'HermesData' and 'RangedHermesData'
RangedHermesData-class 'HermesData' and 'RangedHermesData'
rbind Row Binding of 'AnyHermesData' Objects
rename Renaming Contents of 'SummarizedExperiment' Objects
rename-method Renaming Contents of 'SummarizedExperiment' Objects

-- S --

samples Sample IDs Accessor
samples-method Sample IDs Accessor
set_tech_failure Set Technical Failure Flags
show Show Method for 'AnyHermesData' Objects
show-method Show Method for 'AnyHermesData' Objects
show-method Summary Method for 'AnyHermesData' Objects
subset Subsetting 'AnyHermesData' Objects
summarized_experiment Example 'SummarizedExperiment' Data
summary Summary Method for 'AnyHermesData' Objects
summary-method Summary Method for 'AnyHermesData' Objects

-- T --

test_proportion Check for proportion
top_genes Derivation of Top Genes

-- V --

validate Internal Helper Functions for Validation of 'AnyHermesData' Objects
validate_cols Internal Helper Functions for Validation of 'AnyHermesData' Objects
validate_col_data Internal Helper Functions for Validation of 'AnyHermesData' Objects
validate_counts Internal Helper Functions for Validation of 'AnyHermesData' Objects
validate_names Internal Helper Functions for Validation of 'AnyHermesData' Objects
validate_prefix Internal Helper Functions for Validation of 'AnyHermesData' Objects
validate_row_data Internal Helper Functions for Validation of 'AnyHermesData' Objects

-- W --

wrap_in_mae Wrap in MAE

-- misc --

.ConnectionBiomart Connection to 'BioMart'
.HermesData 'HermesData' and 'RangedHermesData'
.HermesDataCor Correlation between Sample Counts of 'AnyHermesData'
.HermesDataDiffExpr Differential Expression Analysis
.HermesDataPca Principal Components Analysis Calculation
.HermesDataPcaCor Correlation of Principal Components with Sample Variables
.HermesDataSummary Summary Method for 'AnyHermesData' Objects
.HermesDataTopGenes Derivation of Top Genes
.RangedHermesData 'HermesData' and 'RangedHermesData'
.row_data_annotation_cols Annotation Accessor and Setter